Returnal is the first big PS5 exclusive to come since what feels like its launch. It actually might be, I can’t even remember. Lots of people are really enjoying Returnal and for all different reasons.
However, losing progress on your run would definitely not be enjoyable. There’s a Returnal patch on the way and when it goes live, if you’re in the middle of a run you will get bumped and lose your progress if your PS5 is allowed to update.
There is a workaround, though that Housemarque themselves pointed out today.