How to Use Pills in Binding of Isaac Rebirth

Are you looking to level up your Binding of Isaac Rebirth skills? Pills are one of the most important tools in the game, and if you know how to use them correctly, they can give you a huge advantage. In this guide, we’ll be covering everything you need to know about using pills in Binding of Isaac Rebirth.

How to Use Pills in Binding of Isaac Rebirth

use pills in binding of isaac rebirth

Using pills in The Binding of Isaac: Rebirth can help you make your way through the game, but it might not be immediately obvious how to do so. Fortunately, it’s not too difficult once you know the basics. Here’s a quick guide on how to use pills in BoI:R.

First, you’ll need to open the Options menu by pressing and holding the PS button for a few seconds. In this menu, you’ll find an option for ‘Controls.’ Select this, then turn on touch emulation. This will allow you to perform gestures on the screen in order to activate pills and other items.

Once touch emulation has been activated, you’ll be able to use pills by simply tapping the pill icon at the bottom of the screen. This will cause the pill to appear on-screen, along with a randomly generated effect. You can then tap and drag your finger around the screen in order to determine where the effect will take place. Note that some pills have more than one effect – depending on which direction your finger is moving when you release it, different effects may occur.

That’s really all there is to using pills in The Binding of Isaac: Rebirth! It may take some practice to get used to performing gestures quickly and accurately, but once you get the hang of it you should be able to make full use of all the different types of pills available in-game. Good luck!

How to Use Pills Without Touching the Screen

In Binding of Isaac: Rebirth, players can use pills without touching the screen by enabling touch emulation in the system-level options menu.

To do this, players should hold down the PS button for a few seconds to access the menu, and then turn on touch emulation. Once enabled, players will be able to use pills by tapping (not holding) the drop button (by default the left Ctrl button on PC).

This will activate the pill/card slot and allow players to use one-time use red keys placed on the slot. Utilizing this method, players can take advantage of pills without having to worry about accidentally consuming them or having to interact with the screen directly.

Additionally, there are certain strategies for dealing with bad pills, such as using other consumables or taking advantage of certain mods.

Tips and Tricks for Pill Usage

Using pills in The Binding of Isaac: Rebirth can be tricky, but there are some tips and tricks that can help make the experience easier.

For starters, it’s important to remember that the effects of pills change each playthrough and that it can be beneficial to take multiple pills in a row.

It’s also a good idea to enable Touch Emulation if you’re playing on a PC, as this will allow you to use the mouse or keyboard to quickly access pills.

Finally, if you happen to get a bad pill effect, it can be helpful to use runes or cards to cancel out the effect.

With these tips and tricks in mind, you should have a better chance of getting the most out of your pill usage in The Binding of Isaac: Rebirth.


The pill system in Binding of Isaac: Rebirth is a great way for players to keep up with the intense action of the game.

With the ability to use pills without having to touch the screen, it provides a great way for players to stay in control without sacrificing their accuracy or speed. With some practice, players can master the pill system in Binding of Isaac: Rebirth and become unstoppable!


What is I Found Pills in Binding of Isaac?

I Found Pills are random items that can be dropped by enemies, found in chests, or spawned in rooms in the game Binding of Isaac. When consumed, these pills may have different effects on the character.

What does consuming an I Found Pill do?

Consuming an I Found Pill may have different effects on the character. It could change their appearance, create a large yellow pool on the floor that will damage enemies or do poison damage to everything in the room.

How do I use Pill?

To use it, press “Q” while you are on the same floor as the pill. You can also combine it with any cards or runes you may have unlocked in order to increase its potency.

Should I keep unidentified pills until a Q key item shows up?

Yes, it is generally recommended to keep unidentified pills until a Q key item shows up so you can test it after defeating the floor’s boss for maximum effect.

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